Runewords are some of the most impressive items that you can create in Diablo 2: Resurrected, however D2R Ladder Items, they require quite some effort to accomplish. You'll first have to find the correct runes needed to craft the runeword. Afterwards, you'll have to find the weapon either a shield or armor that is able to accept the runeword. The item must have the right number of sockets in order for the runewords to work and the runes must be put into the socketed item in the right order. It must also be unadorned (white) or magic (blue) or rare (yellow) exclusive (gold), as well as set (green) items that have the correct amount of sockets will not work for runewords.
In this regard, you need to take great care when creating a word for a rune. Doubleand triple check that the items's proper type -for example, the Insight runeword could be constructed in polearms or staves, however not spears . You must also lay out the runes in the proper order prior to placing them in the item.
There are some nuances with regard to weapon and armor which you need to be aware of. "Body armor" does not include items that you wear on your the torso. General "armor" includes shields, boots, gloves, helms, etc. Hammers won't work using runewords that are intended for maces Diablo 2 Resurrected Items. "Melee weapons" don't include melee weapons like the crossbow and bow. Orbs, too, aren't considered melee weapons.